Description
Introduction Part I Examples, Frequency, and Consequences 1. What Is Medical Reversal? 2. Subjective Outcomes Why Feeling Better Is Often Misleading 3. Surrogate Outcomes 4. Screening Tests 5. Systems Failure 6. Finding Flawed Therapies on Our Own 7. The Frequency of Medical Reversal 8. The Harms of Medical Reversal Today's Patients, Tomorrow's Patients, and the Health-Care Field Part II 9. A Primer on Evidence-Based Medicine What Is Evidence in Medicine? 10. What Really Made You Better When Evidence Gets Complicated Part III 11. Scientific Progress, Revolution, and Medical Reversal 12. Sources of Flawed Data 13. Why Are We So Attracted to Flawed Therapies? Part IV 14. Medical Education A Very Good Place to Start 15. Academic Medicine 16. Reforming the System The Burden of Proof and Nudging Our Way Past Reversal 17. How Not to Become a Victim of Reversal 18. Beyond Dogma When Randomized Trials Are Unnecessary Acknowledgments Appendix References Index
Vinayak K. Prasad, MD, MPH, is a practicing hematologist-oncologist and internal medicine physician at the National Cancer Institute. Adam S. Cifu, MD, is a professor of medicine at the University of Chicago. He is a practicing general internist, medical educator, and the coauthor of Symptom to Diagnosis: An Evidence-Based Guide.